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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c6f63a49b24785d207d636bb084c85a4e1277639c4f7dd048214a5a4d161a2' 
  AND token = 'FC2OaQz2uX4ibAVZ3Q6DS67Y0ZR3RAXpkwyn9//2U80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}