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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866e1cc6d0aa6ad785c2f6d23dfe9c5533a1190212c83c59a86f86dc249bba48' 
  AND token = '0Pbx9NSOy0DsH422z4MQ51J3wYO1PSKpxtlJcXMENjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}