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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fc4edc51c2b3c1cb9cd530f208f33924c68ac9e7b765f226350d6cdf4d2f22' 
  AND token = 'KP2BUVPrKRDaId6oSG4SEZgNR/zltKM7+swyhmimLdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}