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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0cc14de225e5cdac55a2917fdd87a17c6a0a29dd11bdf7858266d909b8a606' 
  AND token = 'Q3eUYfmomSr8CC1/OYvTqg97GMllo20R8ndaVdL5TME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}