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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6198690deb8a10f459e75284ea81e6f1ef3b12a66b1be1910a774cb710cf167' 
  AND token = 'KwpUnB4c37trMJZVnz9m+XpLeww676MGS7Gye/6nC4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}