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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d2266e27c141ef3248b8b85d5ef3c25fb1a5efb1c158796ac9e2acd0f9f799' 
  AND token = 'RUgqJqZP6zimcHFSssty6vnZN/lKfJg9v7FrZ6DPabo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}