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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb46fa7f216a30654eebb251506fb27b65ad4066d63cf875436663eb9a0af84' 
  AND token = 'n+WBA5mpEJcF8IDrtuvGEg0BHDZlSJsyf0CdX4qd6Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}