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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea04d89bd48e0164ec0314238e1087b4d2bb8f1303a49ffbdc88c500080f340' 
  AND token = '6W1idFSWmWzCYhkbZ514VRdYoVxTZuCvkXnAs/CEPew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}