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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78459a69a348e7d72e82f13ee0a3c25e2b98f0cc8ce39fb03a7d65442e44f12c' 
  AND token = 'VR2J/Cp9FD78s+Cgs+UemQmKknVJYcEZkMk32cKbGAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}