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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c0550e9c78ec299214d56243fe3c2a92ed93dc985600cc610c055d482c79c5' 
  AND token = 'Pg9+8be+nrdtV2sBjpARN7883Tbm2cu5Stta/3NkIZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}