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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb73146dbdcafae85b73a0eb6ce4e98db9ab2db36c17a900b44439c6ba82e4b' 
  AND token = 'VSD19uCOKV3MQ0n3iE97KZ0bs3oObGkpVwdTDz+ZE0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}