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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc9a93107c823eadea431ae12d05a4da3875bfe86306a5e23a29f98ae56a548' 
  AND token = 'vcjoje0ag5Smn67H48VMXFwND2kOz6T592YpyF0/BcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}