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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80890320ed4c6a06c64460e872eff231bd7f985591d312b57e03397fc023d91b' 
  AND token = '//eXy8lH9iXfmwI/AWGU2P+WHlLw8OeZfw/r+uKWyKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}