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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6126686d8bba145c8f7e87bd96dd07d12cfdd4cc45534c6194b090104b1086' 
  AND token = '4SuYJUotjbUj7fwTV+rTLUjFaTEG6Lxv4a+32KddiXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}