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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644b866f72181c3b0e27319a884b701ae6fb56d0eee9897c856171b8394b765d' 
  AND token = 'QQa0TmfXb8RAHZBvH+yhf/MK5Xa3Q2U0NfuQPXK5ATA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}