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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7707b4d34abc651f76cd58fbb2b7e27a7729c51007de2455b6105e7953ab223' 
  AND token = 'lYXikaGJC3oHiqAyk6t+pqnHWyazF59XfyMKQTAbgGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}