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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e372c6aa9e6dc56abcc1ab634be5155f78d74dff3eee521ca98a00ea4db41f' 
  AND token = 'b1Vt7CEKba98XEBzTIEhgRK58rfLOthGBAW8DztOw4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}