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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2205ee3694276dd912ec52a7adf3143ac757f1c9eeda928d8d0e30e448c64171' 
  AND token = 'TgKphE9sdRAKmoCzbW3FXSkUQsE6rNjtZoVj85l7vAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}