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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2854b9bbaf64a722a3016f5a66b34cebb824ac75563a07b562b4bb37cbb5a4' 
  AND token = 'roRM5YSINJM4+PIiTWsZKTorOX41WWC3PrJ7I5ryR/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}