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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef24a9db4c3d94f8f8cf183833f7b2bd468d00aa7bf749f1cede7ca1d6bffc71' 
  AND token = 'dybZ0FobEIujh//ji933AR90msnoG4aVwHZKN/emDtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}