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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afdd9e080211e1ad57647c6d973daa58e299def18dfb62acca7fcf27bd3838d9' 
  AND token = 'qPvlb5F2DrMduuImfQFv162OX+vsZO8ydVFRwvHB2/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}