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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aabb5c6bef580bab5e67294424605ed3f8040478c58c79d5408f55799384af9f' 
  AND token = 'ePA+bEimMQnoyuSzgyPRGQef6jJxg+KDMLru0vmBdwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}