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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b10bc103bcaf90ba74a73a60b437469a662c0f647647fd83a0062d5b8a483f' 
  AND token = '6NfnjaTdIuL5bsZ3H6Rgwx+uspezFF9wjnW7PEgFArI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}