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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c21655137d164ceb4da64cea319ddc4ff8688c9cace1a4a4bae1069e13d96b6' 
  AND token = '79NfK7LbPtGTewrUX92tFWFmwZ55qIuOiD63+aTJpdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}