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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42137ba2d1e30879066eb8e31b1d5b2aaff62b3aa2e5859644653010eb00856d' 
  AND token = 'jg/Amzv8NOVIAxbc/GdFyMHDL8UTgiKHzH7GCs+s0go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}