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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49be637a7c40d077fbcbf9b9682ac2fbcc75f735b8591742f3ec9c9dc3c61189' 
  AND token = 'IC4wHPpi5uSifLOkCxNfZKIIKlA7dAaQM+MK0MSSU+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}