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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aaa473ecd8b6db200f6a56e9cc90df7a33829ea5a86dd19114c8c41c47f4ddb' 
  AND token = 'ItEE0tEDK0INuDqwWJjwvz2MC/vmSmbiFq32xarf7Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}