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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61d3b2d3fadd47fe84d7a8d7da0729fa7da298cab40aabdfa4d868d6d248a74' 
  AND token = 'xrm4B7yuP8H8CYSFpRoQzcKwSbCPJJ4eGU6DSy0GQ7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}