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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8258ad207e85c1d99665273fa059f4ad27163ff6e257e011f7795d59a87d8e' 
  AND token = '+hAYVdIdmOLwV+olOiD+mnTsGSZam+I624xjalDaBX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}