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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d463e206451a09c97d236deb9bc71e522c61b680c60a96776abb1e5e2ae552e' 
  AND token = 'FUrs5bB0DGuku7a4vW11NGxD7QkhgAjS0QHqR4l6daY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}