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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82299bb5a3d8b849d24306084ed9330508de7c185af07b3bb574c2e5b851f826' 
  AND token = 'UM3Ss7ynQLWK5NI710Gx1/0c455UB4dqkcAFzLuLqqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}