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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621fdebba08814a454eb71f8cf8c1a7487a4cb711d1e60c130e1fd346fdb8ffc' 
  AND token = 'sPPyI2xdUEB0z+VfHrhR92DzXDFBP3i4DUYLSHZB39E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}