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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9298540828251372c7a4a038fc527630d31e90f98eae3380c705e34de218f5cb' 
  AND token = 'ux1CYJJl+E0cLnMqC/fQpYfMmOcPeQKGHb4ZanEUaSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}