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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43ad418988b231c1582ffa1fa73313b0bf0f26ccb3936de005f4ab0d36911a9' 
  AND token = 'pKZwVPLZPCRm7pqw2s9r8//33r6jk0cTcFM1Zr0GlJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}