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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9049e90f146ddd4f242ba8cf36c07d007ed6550f4fbdaa467fac0a9a9e723cef' 
  AND token = 'ttn6FMI00/LF5WjEwFJxI8pHWRcbVOOs7KmS4ZUtook=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}