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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e405800d139f9eabc19f888ed861bbaeb54af9af8cfa4d025670a9c87d3b857' 
  AND token = 'pGuqTfaB5uJp6LVMVlGVE8Yw27kY8gcVMNHsO5Q3FMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}