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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66fcbb7da9a6af75b91a0ab6da64ade155d6ff275f380490c14e1e4a3eef426' 
  AND token = 'sUB1TidDRMMF0C7lor75sJwyLy5hFr5SqM8Q1IA7TqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}