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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '559cb1221160ebf4d0d9a3377cba46225ba8a0e5339f5a680c9cfa2cc01f5d37' 
  AND token = 'CA1pJRBI+J0HzJkB+fFcHYId8Q/LWyBtCnHwMc9zAM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}