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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6adc1e793bbbfb32bf6dfbaeb2c20c803e585f1ac55ccbc17ae002407af588' 
  AND token = 'tys/e0e6byZT68fGXcuGzFgpJz/4gSF+T8P/UWrTYcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}