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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d8ab49b0904809c1d1cd16d836eb53e4bef14e1442835f8079d3dcc42c86e9' 
  AND token = 'fgbD5L7eMCHptigFnv9MMHE6MH3uvKZ6cLvDjBOkoVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}