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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eab907bdf92d0a1a8f31cd3cfc521c9ed5199a1a432f0e36ca4108b7be65c2f' 
  AND token = 'o1eNx5d3+aogpd3ElOLK3TD43NpRunEmQ+DUC3vrGvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}