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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746a7a4bb470c1dee5b9141aaf218eafc27268adbbc4c14d979c4ae99e898c1a' 
  AND token = 'qb7rVW9ztU9YBwKAOh4RxHi5x2lKFUhr3kyQe5tHw3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}