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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9da3975dca3497d12b91c158a169333d64e8b89f5207e00580139f8fd00e07' 
  AND token = 'Mhpb2EeFk7oO8T7VA2X+IvxEL0H9bdXM480fPZe9xmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}