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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffbe5f94c01cff4585430b2f34253d7d6b3a3d47694b42405ebe1dc9249ed54c' 
  AND token = 'EuVt7zktrYsNXiXXpwSMjkuL0KnrDk2WaTmmqq1IWrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}