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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a70ffc97641b17c8350258369a31e53ae6b1bacbe9dd9c2163f7affdd5d86b6' 
  AND token = 'EDxWFrzP6FanMnpXFFTbbA3oVVdgiPhmO6ZfS76kIxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}