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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb564ae04a737cc797e69d2f3d42a4cce5c6a7321881ae64b3300b3f9ec9171' 
  AND token = 'ZpIYVWA/3A6cmelyU6WKT1t/qGS/rkZgYAGiyXIMTZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}