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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4bf27dbc36ebbc861a5b8584e8b2cc2c2e108d7b209968695ecac67f213f64' 
  AND token = 'MBFxFCWDIb71vPT8m/N5d5RKiGBpwTIr9Gq2pZzfcZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}