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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a421b30fb5e3b229e340782c52a978e5eed5bac235c5fc341ce4c2737b1ee3' 
  AND token = 'LZ4tw3sB/O2dmpa/shGSRrm9I/KuTCWjVIIplSSmkxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}