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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb468a72e4597ccb25ffbb9a7d24501f3e3ee8e0c9c70c16f45491aa6ece20d' 
  AND token = 'sj59YO3H+FhYrEcVJ740CB9+LpWJJ1iZOVybBPVlmsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}