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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27b5b0c2f5b05aac4f33d40c5a6db1b8f54c8c9c9c8e419e560dbfc542bc770' 
  AND token = '0aZKlmCuFgZ10uWErtWvQixyDgq2kRfTI+eQuJfYDFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}